Effect of sodium cromoglycate on histamine induced bronchoconstriction and exercise-induced asthma.
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چکیده
منابع مشابه
Effect of verapamil and sodium cromoglycate on leukotriene D4 induced bronchoconstriction in patients with asthma.
Leukotriene D4 (LTD4) may be an important mediator in asthma. The effect of verapamil and sodium cromoglycate on LTD4 induced bronchoconstriction has been examined in seven patients with asthma. The bronchoconstrictor response to increasing concentrations of inhaled LTD4 (0.0032-50 micrograms/ml) was assessed by measuring changes in FEV1, specific airways conductance, and flow rate at 30% of vi...
متن کاملEffect of ipratropium bromide and/or sodium cromoglycate pretreatment on water-induced bronchoconstriction in asthma.
The mechanisms underlying water-induced bronchoconstriction are still not fully understood. Cholinergic reflexes and mast cell mediator release are currently believed to play an important pathogenetic role. In order to evaluate the relative contribution of each of these mechanisms, we studied the effect of ipratropium bromide (80 micrograms), a muscarinic antagonist, and sodium cromoglycate (20...
متن کاملSodium cromoglycate and ipratropium bromide in exercise-induced asthma.
In thirteen patients with extrinsic asthma the effects of placebo, sodium cromoglycate, ipratropium bromide, and ipratropium bromide plus sodium cromoglycate were studied in a random double-blind fashion to assess their inhibitory action in exercise-induced asthma (EIA). Exercise testing consisted of steady state running on an inclined treadmill for up to eight minutes. In eight of the 13 patie...
متن کاملDose-response study of sodium cromoglycate in exercise-induced asthma.
Ten patients with exercise-induced asthma participated in a single-blind dose-response study comparing the protective effect of inhaled sodium cromoglycate in increasing concentrations from 2 to 40 mg/ml. Saline was used as a control. Effects were assessed from the mean maximal percentage fall in forced expiratory volume in one second (FEV1) after the patients had run on a treadmill for eight m...
متن کاملIs Exercise-Induced Bronchoconstriction Exercise-Induced Asthma?
The article in this issue of RESPIRATORY CARE by Burnett et al1 reports that 34 of 80 college athletes had exerciseinduced bronchoconstriction (EIB), most in the absence of symptoms. The authors further suggest that these athletes are at risk and that the identification of those with EIB may prevent morbidity and mortality. The implication is that the presence of EIB is evidence for asthma. But...
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ژورنال
عنوان ژورنال: Nihon Kikan Shokudoka Gakkai Kaiho
سال: 1984
ISSN: 0029-0645,1880-6848
DOI: 10.2468/jbes.35.399